Biological Sex Claims Annika Gompers, Ann Caroline Danielsen, Sarah S. Richardson Biological Sex Claims Annika Gompers, Ann Caroline Danielsen, Sarah S. Richardson

New Video: Gender Inequities in Sports and ACL Injury Risk

As the 2026 Winter Olympics kick off with projected record-setting representation of women athletes, the GenderSci Lab is excited to share a video explainer of how gendered social factors contribute to a higher risk of injury for women athletes. 

Using animations and short interviews with GenderSci Lab researchers, the video unpacks our recent research paper in the British Journal of Sports Medicine demonstrating how factors related to the history of underinvestment in women's sport such as smaller team sizes and lower ratios of practice to competition time may drive observations of higher rates of ACL injuries in women athletes. 

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STS, Biological Sex Claims Kelsey Ichikawa and Sarah S. Richardson STS, Biological Sex Claims Kelsey Ichikawa and Sarah S. Richardson

Sex in the Medical Machine: The GenderSci Lab Analyzes the Algorithmic Future of Sex-Based Medicine

In a peer-reviewed paper recently published in Big Data and Society and led by Kelsey Ichikawa and Marion Boulicault, GenderSci Lab members explore the use of sex stratification in applications of machine learning in medical research and argue that current practices risk embedding biological sex essentialist assumptions into medical science. These practices include the creation of distinct algorithms for males and females (what we call “pink and blue algorithms”), the use of machine learning to identify distinct male and female patterns in disease, and the incorporation of gender/sex variables as predictors in algorithms for disease risk and detection. 

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Biological Sex Claims Ben Maldonado, Hannah Niederriter Biological Sex Claims Ben Maldonado, Hannah Niederriter

Science without Sex Essentialism? As Easy as 1, 2, 3!

Over the course of nearly a decade, the GenderSci Lab (GSL) has developed incisive analyses, approaches, frameworks, and methods for thinking critically about sex and gender in biomedicine. Our new article “Three Maxims for Countering Sex Essentialism in Scientific Researchin the journal Biology of Sex Differences synthesizes lessons from GSL research into concrete and portable recommendations for biomedical researchers. Through the examples of gender/sex disparities in adverse drug events, COVID-19, and anterior cruciate ligament (ACL) injury, we offer guidance for avoiding the pitfalls of sex essentialism and producing better science. The article is designed for researchers, reviewers, and editors aiming to produce more rigorous science as well as for instructors and students at the undergraduate or graduate level interested in exploring common problems in sex essentialist research. 

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Biological Sex Claims Sarah Richardson Biological Sex Claims Sarah Richardson

A History of Sex, Gender, and Medical Expertise in the New England Journal of Medicine

This week, members of the GenderSci Lab published a new piece in the New England Journal of Medicine. Authored by the Lab’s historians of medicine and science, Ben Maldonado, Jamie Marsella, Abbie Higgins, and Sarah Richardson, this piece traces how authors in the Journal articulated harmful ideas of innate sex difference.

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Biological Sex Claims, SABV Sarah Richardson Biological Sex Claims, SABV Sarah Richardson

New article in Cell: Calling for Rigor and Precision in the Study of Sex-Related Variables

Our piece in this Cell special issue considers how, in the context of policies mandating the consideration of sex (such as the NIH’s Sex as a Biological Variable policy), basic scientists can operationalize, analyze, and interpret sex-related variation in ways that achieve conceptual and statistical rigor, as well as precision in how such knowledge is applied in the clinic and beyond. 

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Biological Sex Claims Sarah Richardson Biological Sex Claims Sarah Richardson

New article: “Making a ‘Sex-Difference Fact’”

This week, the GenderSci Lab has a new paper out in Social Studies of Science, “Making a ‘Sex-Difference Fact’: Ambien Dosing at the Interface of Policy, Regulation, Women’s Health, and Biology (open access).” The paper analyzes the first drug ever to be issued with an FDA mandated differential dose for men and women on the drug’s label.

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Biological Sex Claims, Law and Policy GenderSci Lab Biological Sex Claims, Law and Policy GenderSci Lab

Bostock, the HHS Rule, and Legal Reliance on Biological Claims about Sex: An Analysis from the GenderSci Lab

Last week was big news for LGBTQ+ rights in the US. Two major pieces of law came out just days apart, changing the landscape of sex-based anti-discrimination law and the way sex is understood in federal law. In this post, we briefly outline these new legislative policies, consider the implications for LGBTQ+ rights in the US, and think about how this changes legal reliance on biological claims about sex.

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Biological Sex Claims GenderSci Lab Biological Sex Claims GenderSci Lab

Theory Matters: Sex, Gender, and Alzheimer’s Disease

The SWHR task force operationalizes ‘sex’ and ‘gender’ as research variables with sweeping explanatory potential in biomedicine. The manner in which they do so reveals a theoretical gulf between a widely practiced genre of bioscience knowledge production in women’s health research and critical feminist approaches to science, medicine, and the body.

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